N Terminus of Type 5 Adenylyl Cyclase Scaffolds Gs Heterotrimer
نویسندگان
چکیده
منابع مشابه
N terminus of type 5 adenylyl cyclase scaffolds Gs heterotrimer.
According to accepted doctrine, agonist-bound G protein-coupled receptors catalyze the exchange of GDP for GTP and facilitate the dissociation of Galpha and Gbetagamma, which in turn regulate their respective effectors. More recently, the existence of preformed signaling complexes, which may include receptors, heterotrimeric G proteins, and/or effectors, is gaining acceptance. We show herein th...
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ژورنال
عنوان ژورنال: Molecular Pharmacology
سال: 2009
ISSN: 0026-895X,1521-0111
DOI: 10.1124/mol.109.058370